In the second quarter of 2024, the US FDA's official website updated the GRAS status of 19 products. Among these, one substance was approved, while 18 are still under review.
This article provides a summary of the US FDA Generally Recognized As Safe (GRAS) acceptance and approval status in the second quarter of 2024.
Approved FDA GRAS substance in the second quarter of 2024 (FDA has no questions)
S.N. | GRN No. | Substance | Date of approval | Notifier |
1 | 1155 | 1-methylcyclopropene | April 23, 2024 | Fresh Inset S.A. (Poland) |
Pending substances in the second quarter of 2024
S.N. | GRN No. | Substance | Notifier |
1 | 1164 | A chemically synthesized analog of pediocin PA-1 specific to Listeria monocytogenes | Innodal and Quality Systems Solutions (Canada) |
2 | 1165 | (R)-1,3-butanediol | Genomatica, Inc. (U.S.) |
3 | 1166 | Fava bean (Vicia faba L.) protein hydrolysate | Nuritas (Ireland) |
4 | 1167 | Brazzein produced by Komagataella phaffii expressing a gene encoding for brazzein from Pentadiplandra brazzeana | Perfect Day, Inc. (U.S.) |
5 | 1168 | Tigernuts flour | Tigernut Traders, SL (Sprain) |
6 | 1169 | 6’-sialyllactose sodium salt | GeneChem, Inc. (Republic of Korea) |
7 | 1170 | Resistant dextrin from tapioca in powder or syrup form | Icon Foods, Inc. (U.S.) |
8 | 1171 | Non-animal type 21 collagen polypeptide | Geltor, Inc. (U.S.) |
9 | 1172 | Liquid milk, either whole or nonfat, combined with lactose and water | Synlait Milk Limited (New Zealand) |
10 | 1173 | Invertase enzyme preparation produced by Trichoderma reesei expressing a gene for invertase from Aspergillus niger | AB Enzymes Inc. (U.S.) |
11 | 1174 | Dry whole goat milk | The LittleOak Company (U.S.) |
12 | 1175 | Lactiplantibacillus plantarum DSM 23881 | Nordwise BioCC OÜ (Estonia) |
13 | 1176 | Lacto-N-tetraose | FrieslandCampina Ingredients B.V. (The Netherlands) |
14 | 1177 | Bacillus coagulans “Unique IS-2” spore preparation | Unique Biotech Limited, India (India) |
15 | 1178 | Rebaudioside I obtained by enzymatic treatment of steviol glycosides purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni (rebaudioside I) | Sichuan Ingia Biosynthetic Co., Ltd (China) |
16 | 1179 | Liquid whole cow milk | Crossway Foods, Ltd. (Ireland) |
17 | 1180 | Cellobiose | SAVANNA Ingredients GmbH (Germany) |
18 | 1181 | Weizmannia coagulans LMG S-31876 spore preparation | Abode Biotec India Private Limited (India) |
Source: The inventory of GRAS notices.
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Further Information
Summary of US FDA GRAS Acceptance and Approval Status in the First Quarter of 2024