SCCS Issued Final Opinion on the Safety of Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165)

On March 5, 2023, the Scientific Committee on Consumer Safety (SCCS) of the European Union issued a final opinion on Hydroxypropyl p-phenylenediamine and its dihydrochloride salt (A165)(SCCS/1659/23). The preliminary opinion was released on December 7, 2023.

The SCCS concludes the following:

1. In light of the data provided, does the SCCS consider Hydroxypropyl p-phenylenediamine and its dihydrochloride salt safe when used in oxidative hair colouring products up to a maximum on-head concentration of 2 %?

In light of the data provided, the SCCS considers that hydroxypropyl p-phenylenediamine and its dihydrochloride salt are safe when used in oxidative hair colouring products up to a maximum on-head concentration of 2%.

2. Does the SCCS have any further scientific concerns with regard to the use of Hydroxypropyl p-phenylenediamine and its dihydrochloride salt in cosmetic products?

A mild to moderate eye irritation potential of the test item cannot be excluded. Hydroxypropyl p-phenylenediamine and its dihydrochloride salt is a moderate skin sensitiser based on animal data.

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Further Information

SCCS/1659/23