The health risk assessment report of pesticides is not only an important part of pesticide registration materials but also an important basis for ICAMA to decide whether to approve pesticide registration in China. Scientifically speaking, pesticide health risk assessment is based on scientific data and models – scientifically evaluating the possibility and severity of adverse effects of pesticides on human health under specific conditions. This article summarizes the key technical points and precautions in conducting pesticide health risk assessment in China.